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2024 09 12 P10 Client Intelligence Email Report

2024-09-12 - P10 Client Intelligence Email Report

Oct 04, 20253 min read

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September 12, 2024

Hello team, Please find our social listening snapshot below for 08/30 - 09/12, along with a dashboard snapshot PDF attached.

LEO Pharma

Top LEO Pharma Company & Drug Discussions

  • Company Mentions:
    • LEO Pharma presents data from its CHECK and RWEAL studies at the ESCD 2024 Congress, finding that CHE occurs in approximately 5.6% of people, with one in five people attributing the condition to their occupation. (Also mentioned in Drug Topicsand The Dermatology Digest)
    • The industry continues to cover the failed Phase III trial (ASCEND) of TMB-001 for ichthyosis.
  • tralokinumab (ADBRY):
    • MotherToBaby promotes enrollment of its observational study of ADBRY in pregnant people.
    • In its latest quarterly report, a market research firm monitoring the AD market mentions that “despite a mixed initial reception, ADBRY has significantly grown and now competes closely with RINVOQ, whose usage has plateaued since 2022.”
    • A discouraged patient on Reddit mentions both DUPIXENT and ADBRY not working for their Eczema.
  • delgocitinib:
    • Medical Dialogues, Infectious Disease Advisor, and Dermatology Advisor report on the DELTA 1 and DELTA 2 trial results of delgocitinib for CHE.

Other top Atopic Dermatitis (AD) & Chronic Hand Eczema (CHE) Discussions

  • A comprehensive review and meta-analysis found that EBGLYSS (lebrikizumab) showed similar efficacy to DUPIXENT (dupilumab) in improving signs, symptoms, and quality of life for adult patients with AD.
  • HCPLive publishes new episodes on treatment advances and evolving standards in AD:
    • Changing Standard of Care in Atopic Dermatitis
    • Unmet Needs and Gaps in AD
    • Looking Beyond Type 2 Inflammation in Atopic Dermatitis
    • JAK Inhibitors in Atopic Dermatitis
  • According to research from GlobalData, the AD market is expected to reach $16.7bn by 2030.
  • A safety update for CIBINQO (abrocitinib) shows no new safety issues over nearly 4 years of use for AD, but finds that older patients are more likely to experience serious adverse events.
  • Lynk Pharmaceuticals reports positive data from its Phase Ib clinical trial of JAK inhibitor LNK01004 for the treatment of AD.
  • A case report of an AD patient who received the Pfizer-BioNTech COVID-19 vaccine recognizes erythroderma as a potential adverse effect of COVID-19 vaccination.
  • According to a new study, fish oil supplementation during pregnancy was associated with children having a lower or higher risk for developing AD, depending on the mother’s genotype.

Dr. Reddy’s Laboratories

  • Company Mentions:
    • Dr. Reddy’s recalls Ibuprofen tablets in the US due to failed impurities/degradation specifications.
    • China bans an ADHD medication manufactured by Dr. Reddy’s, after government inspectors discover manufacturing problems.
    • Dr. Reddy’s partners with Kainomyx for the development and commercialization of an affordable anti-malarial drug in in the U.S., Europe and in low and middle-income countries.
  • denosumab:
    • 2 Minute Medicine reports on the recent study linking denosumab to an increased risk of osteonecrosis of the jaw (MRONJ).
  • We did not find any US discussions about COYA 302, DRL_RI (rituximab biosimilar), or DRL_TC (tocilizumab biosimilar).

Paratek Pharmaceuticals

  • Company Mentions:
    • On LinkedIn, an intern for Paratek shares her positive experience working on projects relating to NUZYRA.
  • omadacycline (NUZYRA):
    • On Reddit, a user inquires about omadacycline for the treatment of Mycoplasma Genitalium, with minimal feedback.
    • In another thread within the same subreddit, a moderator mentions omadacycline as an experimental treatment, but users appear to have little knowledge about the drug.

Graph View

  • September 12, 2024
  • LEO Pharma
  • Top LEO Pharma Company & Drug Discussions
  • Other top Atopic Dermatitis (AD) & Chronic Hand Eczema (CHE) Discussions
  • Dr. Reddy's Laboratories
  • Paratek Pharmaceuticals

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